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Prevalence of high-risk human papillomavirus infection among women in Shaanxi province of China: A hospital-based investigation.

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机构： [1]Department of Gynecology and Obstetrics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China. [2]Department of Gynecology and Obstetrics, The Affiliated Hospital of Xi'an Medical College, Xi'an, Shaanxi, China. [3]Department of Gynecology, The Affiliated Yan An Hospital of Kunming Medical University, Kunming, Yunnan, China.

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关键词： cervical cancer genotype distribution high-risk human papillomavirus prevalence

摘要：

This study aimed to investigate the characteristics of female high-risk human papillomavirus (HR-HPV) infection in Shaanxi province of China. A total of 14 111 women were enrolled for HPV genotyping test, and a cytology, and/or cervix biopsy were performed in partial women. Of these women, the HPV infection rate was 30.21%, and 26.73% were caused by HR-HPV. The most common HR-HPV genotypes were HPV-16, HPV-58, HPV-52, HPV-18, and HPV-31. The prevalence of HR-HPV among women older than 50 years was significantly higher than the other groups (P < 0.05). The main carcinogenic genotypes were HPV-16, HPV-18, HPV-58, HPV-52, and HPV-31. HPV-16 and HPV-18 combined caused 80.79% of cervical cancer cases. The infection with multiple HR-HPVs was not a risk factor for cervical lesions. In conclusion, HPV infection was common among women in Shaanxi province. Women older than 50 years were a high-risk group for HR-HPV infection and cervical cancer. HPV-16 and HPV-18 were the main carcinogenic genotypes in this region. © 2016 Wiley Periodicals, Inc.

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出版当年[2017]版：

大类 | 4 区医学

小类 | 4 区病毒学

最新[2023]版：

大类 | 3 区医学

小类 | 3 区病毒学

第一作者：

第一作者机构： [1]Department of Gynecology and Obstetrics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

通讯作者：

通讯机构： [1]Department of Gynecology and Obstetrics, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China. [*1]Department of Gynecology and Obstetrics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, China

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