Periplanosides A-C: new insect-derived dihydroisocoumarin glucosides from Periplaneta americana stimulating collagen production in human dermal fibroblasts
机构：[1]State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China[2]College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China[3]Sichuan Gooddoctor-Panxi Pharmaceutical Co., Ltd, Xichang 615000, China[4]The First People’s Hospital of Yunnan Province, Kunming 650032, China云南省第一人民医院
Three new dihydroisocoumarin glucosides, termed periplanosides A-C (1-3), a known analog, pericanaside (4), and the other twenty known compounds were isolated from the insect Periplaneta americana. Their structures including absolute configurations were determined by comprehensive spectroscopic analyses and computational methods. Biological evaluation showed that compound 2 could stimulate collagen production by 31.2% in human dermal fibroblasts-adult (HDFa) at the concentration of 30M, indicating its significance in skin repair and ulcer.
基金：
Sino-German International Collaboration Project from Yunnan Province of China [2009AC011]; State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources; Center of Cooperative Innovation for South China Medicine of Yunnan Province
第一作者机构：[1]State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China[2]College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
通讯作者：
通讯机构：[1]State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China[2]College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
推荐引用方式(GB/T 7714)：
Yang Yong-Xun,Luo Qi,Hou Bo,et al.Periplanosides A-C: new insect-derived dihydroisocoumarin glucosides from Periplaneta americana stimulating collagen production in human dermal fibroblasts[J].JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH.2015,17(10):988-995.doi:10.1080/10286020.2015.1047771.
APA：
Yang, Yong-Xun,Luo, Qi,Hou, Bo,Yan, Yong-Ming,Wang, Yue-Hu...&Cheng, Yong-Xian.(2015).Periplanosides A-C: new insect-derived dihydroisocoumarin glucosides from Periplaneta americana stimulating collagen production in human dermal fibroblasts.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,17,(10)
MLA：
Yang, Yong-Xun,et al."Periplanosides A-C: new insect-derived dihydroisocoumarin glucosides from Periplaneta americana stimulating collagen production in human dermal fibroblasts".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 17..10(2015):988-995
