机构：[1]Key Laboratory of AIDS Immunology of National Health and Family PlanningCommission, Department of Laboratory Medicine, The First AffiliatedHospital, China Medical University, Shenyang 110001, People’s Republic ofChina[2]Collaborative Innovation Center for Diagnosis and Treatment ofInfectious Diseases, Hangzhou, People’s Republic of China[3]University ofNorth Carolina at Chapel Hill, Project-China, No.2Lujing Road, Guangzhou510085, People’s Republic of China[4]Guangdong Provincial Center for SkinDiseases and STIs Control, Guangzhou 510085, People’s Republic of China[5]Kirby Institute, the University of New South Wales, Sydney, NSW 2052,Australia[6]Department of Epidemiology, Fielding School of Public Health,University of California, Los Angeles 90095, USA[7]Jiangsu Provincial Centersfor Disease Control and Prevention, Nanjing, China[8]He’nan ProvincialCenters for Disease Control and Prevention, Zhengzhou, China[9]YunnanProvincial Centers for Disease Control and Prevention, Kunming, China[10]Shanghai Municipal Centers for Disease Control and Prevention, Shanghai,China[11]Hu’nan Provincial Centers for Disease Control and Prevention,Changsha, China[12]Shandong Provincial Centers for Disease Control andPrevention, Jinan, China
Recent upsurge of new HIV infections among men who have sex with men (MSM) is a major concern in China. Paucity of national-level information regarding the burden and predictors of this progressive epidemic of new infections called for a multi-centric, timely and comprehensive investigation.
Mixed methods were used to recruit MSM from seven cities in China between 2012 and 2013. Recent and established HIV infections were estimated by Western Blot and BED HIV-1 capture enzyme immunoassay. Syphilis and herpes simplex virus-2 (HSV-2) were also tested.
A total of 4496 eligible MSM were recruited. The majority was aged ≤35 years (77.5 %), migrants (60.3 %), never married (69.8 %), and played receptive role in anal sex (70.5 %). The HIV prevalence was 9.9 %, and 41.9 % were recently infected, with sensitivity/specificity adjusted HIV incidence of 8.9 (95 % CI: 7.6-10.2)/100 Person-Years. The prevalence of history HSV-2 and syphilis were 12.5 % and 8.5 %, respectively. Recent HIV infection was associated with having multiple male partners (aOR = 1.4, 95 % CI 1.1-1.9), recreational drug use (aOR = 2.2, 95 % CI 1.6-3.0), anal bleeding (aOR = 2.1, 95 % CI 1.4-3.0), syphilis infection (aOR = 2.8, 95 % CI 1.9-4.3) and history HSV-2 infection (aOR = 2.3, 95 % CI 1.5-3.3).
High rate of recent HIV infection is potentially resulting in progressive deterioration of the overall HIV epidemic among MSM in China. Targeted interventions to address high-risk MSM including those having multiple partners, history of recreational drug use and syphilis or HSV-2 infection seemed to be the need of the hour.
基金：
Mega-Projects of national science research
for the 12th Five-Year Plan (2012ZX10001-006), China-Gates Foundation
(2012), Liaoning Educational Department project (LZ2014038), and NIH
(NIAID 1R01AI114310, FIC 1D43TW009532).
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2016]版：
大类|3 区医学
小类|3 区传染病学
最新[2023]版：
大类|1 区医学
小类|1 区热带医学2 区传染病学2 区寄生虫学
第一作者：
第一作者机构：[1]Key Laboratory of AIDS Immunology of National Health and Family PlanningCommission, Department of Laboratory Medicine, The First AffiliatedHospital, China Medical University, Shenyang 110001, People’s Republic ofChina[2]Collaborative Innovation Center for Diagnosis and Treatment ofInfectious Diseases, Hangzhou, People’s Republic of China
共同第一作者：
通讯作者：
通讯机构：[1]Key Laboratory of AIDS Immunology of National Health and Family PlanningCommission, Department of Laboratory Medicine, The First AffiliatedHospital, China Medical University, Shenyang 110001, People’s Republic ofChina[2]Collaborative Innovation Center for Diagnosis and Treatment ofInfectious Diseases, Hangzhou, People’s Republic of China
推荐引用方式(GB/T 7714)：
Xu Jun-Jie,Tang Wei-Ming,Zou Hua-Chun,et al.High HIV incidence epidemic among men who have sex with men in china: results from a multi-site cross-sectional study.[J].Infectious Diseases of Poverty.2016,5(1):82.doi:10.1186/s40249-016-0178-x.
APA：
Xu Jun-Jie,Tang Wei-Ming,Zou Hua-Chun,Mahapatra Tanmay,Hu Qing-Hai...&Shang Hong.(2016).High HIV incidence epidemic among men who have sex with men in china: results from a multi-site cross-sectional study..Infectious Diseases of Poverty,5,(1)
MLA：
Xu Jun-Jie,et al."High HIV incidence epidemic among men who have sex with men in china: results from a multi-site cross-sectional study.".Infectious Diseases of Poverty 5..1(2016):82
